Sibelius™: MyceliAid newest launch gets a non-GMO certificate

Looking for a research baked ingredient for immunity and skin that’s non-GMO?

Sibelius™ Natural Products launched their newest ingredient Sibelius™: MyceliAid in 2020 to target immunity and skin health trends. Sibelius™: MyceliAid is high quality and scientifically evidenced full-spectrum Chaga extract developed to promote skin health, support immune function and overall wellness. The functional ingredient is also sustainably grown, traceable and suitable for several delivery formats.

Genetically Modified Organisms (GMOs), are plants, animals or microorganisms whose genetic material (DNA) has been altered in a way that does not occur naturally. Over the past few years, GMO crops and foods have raised concern among consumers for their impact on the environment, human and animal health1, 2. This growing awareness means that there is an increasing demand for GMO-free, all-natural alternatives, as well as transparency regarding an ingredient’s origin, cultivation, production, processing, storage and distribution3.

“MyceliAid is our latest launch into the functional ingredient field” explains Arti Gupta, Operations Director at Sibelius “What makes our ingredients unique is the strong science platform we use to select them. Chronoscreen™ is our patented tool we used to confidently select the best ingredient from the best source for our Chaga”.

When discussing the non-GMO process, Arti described that “Sibelius™: MyceliAid will join both our Sage and Chamomile to be verified by the FoodChainID Non-GMO Global Standard. This industry benchmark ensures that our ingredients have undergone risk assessments, traceability, sampling and testing, to verify their compliance with the non-GMO Standard.”

Sibelius is delighted that MyceliAid has obtained the non-GMO Project Verified seal, and will continue to develop natural ingredients of the highest quality, efficacy and safety.

Contact us today to get your sample:


Traceability with Sibelius™: Sage

Sage clinical trial ageing gracefullyTraceability is not just of major importance for us here at Sibelius, but it is also a growing trend amongst consumers. From high-quality sources and processes to fair and responsible supply chains, understanding the steps our extracts take from field to consumer is a part of our key quality processes.

FIRST THINGS FIRST: INTRODUCING SAGE 

Our Sibelius™: Sage (aka the king of botanicals) is our branded, scientifically evidenced and clinically proven dried sage extract, specially developed to enhance memory & attention, and maintain brain health. 

SCIENCE TO DETERMINE DIRECTION

Before we can talk through the steps in our supply chain it’s important to understand why we’ve selected perennial Salvia officinalis for our ingredient. Clonally propagated from root cuttings, our extract of sage was determined the best ingredient from the best source for life extension.

One of the biggest problems manufacturers’ can have is understanding which particular ingredient and then which particular source will produce the best biological activity to aid human health. Here at Sibelius, our patented testing process Chronoscreen™ allowed us to test across multiple sources to ensure sustainability and quality to get to the sage we use today.

FULL TRACEABILITY 

This journey of discovery allowed us to select a particular sage extract grown in the damp, sunny hills of Hampshire, UK. The Sage we use is derived from a proprietary European herb source and cultivated exclusively for Sibelius Natural Products.

The sage leaf is grown and supplied by an experienced and reputable producer under an exclusive supply agreement. All production, including harvesting, is carried out accordingly to defined protocols with full traceability of the crop at every stage.

The next step of our sages’ journey is the extraction process for the bioactive components. To do this we use a manufacturing plant in Herefordshire, UK. Here, we’re able to track all quality and regulatory processes to ensure all the material that’s shipped is of the highest quality for our customers.

SIBELIUS NATURAL PRODUCTS 

At Sibelius, we work closely with our supply chain to ensure our customers have access to the best possible ingredients from the best possible sources. Our research and quality testing provide our customers with the confidence to make marketing changing products.

Our Sibelius™: Sage can be incorporated into a wide range of formats, contact us today to see how our clinically studied ingredients can drive sales.



Plant powered, science driven & built for brains

Brain health is a major trend that isn’t slowing down. Research shows the supplements market for brain health is worth £7 billion in 2020 and it is set to grow at a CAGR of 8%. Consumers are after health products to support their brains, that really work. We’re excited to share that our customer, Clutch Cognition has just launched their healthy energy drink for brains using our clinically proven ingredient, Sibelius™: Sage.

CLUTCH COGNITION - BUILT FOR BRAINS

Home of the next-generation functional drink, Clutch Cognition pride themselves in looking to change the world for the better with healthy, functional nutrition. Meeting the consumer demand for convenience formatting, Clutch Cognition provides a tasty way for consumers to reap the brain-boosting benefits.

Their team of experts and scientists chose our Sibelius™: Sage to add proven, clinically backed, data to their drink that not only fuels brains but also supports overall wellbeing. Sibelius™: Sage is our patented, fast-acting, natural lift to cognitive performance for consumers seeking a non-caffeinated, clinically proven natural boost. 

WATCH IT TO BELIEVE IT

Rune RØnhave Laursen, Clutch Cognition CEO & Founder and David Foreman, aka the Herbal Pharmacist®, discuss Clutch Cognition's launch in our latest webinar. In the clip below, the pair discuss the demand for natural, caffeine-free alternatives for energy drinks, offering sage advice on the importance of healthy functional nutrition.

 

DOWNLOAD THE SIBELIUS™:SAGE WHITEPAPER:



Using science to determine product development direction

At Sibelius, we pride ourselves on supporting our customers through the research and development of consumer health products. The main statement on our website describing our Chronoscreen™ platform is ‘looking for science to determine your development direction?’ because the platform gives managers the ability to clearly determine the best source and best ingredients to invest into. Chronoscreen™ provides the data on life extension to determine the sources and ingredients worthy of additional spend to develop further.

WHY SHOULD YOU BE USING CHRONOSCREEN™?

Chronoscreen™ provides a powerful platform for the screening and identification of biologically active natural products that have the potential for development into ingredients that are beneficial to human health.

  • Gain invaluable insights on complex extracts to drive further decision making and manage risk before committing to expensive clinical trials
  • Gain a competitive advantage for finished products and formulations with access to a new level of understanding of extracts
  • Expand product pipelines with new evidence-based product innovation and suggest potential synergistic combinations
  • Give products a route to patent protection by highlighting the distinction between biologically active ingredients

WHAT MAKES CHRONOSCREEN™ UNIQUE?

Testing for biometric indicators of ingredients offers many benefits to businesses. However, when looking at different types of assay testing, a key consideration is to understand exactly what the testing performs and on what kind of extracts.

One of a kind with C.elegans

Chronoscreen™ utilizes the roundworm, Caenorhabditis elegans (C. elegans), a whole organism model with many physiological similarities to humans including a digestive and nervous system. The validity of the C. elegans model for biomedical research was even recognised by the award of the 2002 Nobel Prize in Physiology or Medicine7.

Many of the pathways known to affect the biological processes associated with ageing and longevity have been conserved through history across a range of species; thus allowing meaningful, transferrable results to be obtained from model organisms and applied to human biology2.

The whole organism approach

The Chronoscreen™ platform can be successfully applied for biological testing of a broad range of natural ingredients. It can identify and confirm the evidence of their potential health benefits, from which we can then determine the pathways essential for the ingredient’s activity. This helps to address consumer demands and concerns as well as regulatory and policy issues.

Each ingredient has a chemical fingerprint that can be used to determine the biometric indicators. What makes Chronoscreen™ unique is that our platform allows us to test whole extracts. The C.elegans are not only able to eat the whole ingredient, but they’re also able to diffuse the ingredients directly into their cuticles, which allows us to monitor the life extension of the chemical fingerprint working together; whilst many other testing platforms are only able to test singular components at a time.

Sibelius validity

Chronoscreen™ can be summarised into three main stages: identification of botanicals, selecting sources, and validating the selected sources. Our process allows us to work with our customers every step of the way to ensure the best, validated, results possible to drive confident direction.

TRIED AND TESTED

Sibelius Natural Products has already tested more than 750 natural ingredients and products and on the back of these tests, we have confidently launched four ingredients that showed superior life extension. At Sibelius, our team of experts are on hand to guide you through the process

 

 

Contact us to learn how Chronoscreen™ can drive your ingredient research and development forward.



Hi & Fi Asia

Hi & Fi Asia is China's leading tradeshow for health and food ingredients. With more than 100,000 predicted visitors and 2,000 exhibitors Sibelius are proud to be represented on the CareLife® stand this year at booth number 41E75. 

23rd - 25th June | Booth 41E75

More information about the event can be found here


Sage clinical trial ageing gracefully

Ageing gracefully with Sibelius™: Sage

Sage ageing gracefully podcast

With no signs of slowing down, brain health has been a key trend in recent years. From improving memory in young adults to stopping the natural decline in brain function as we age; keeping our brains healthy is a priority across a wide range of consumers.

Gerald Quigley Pharmacist & Master Herbalist and David Foreman (aka The Herbal Pharmacist®) discuss ageing gracefully in our new podcast series with Barrington Nutritionals. In the podcast the dynamic duo discusses what ageing gracefully means to them, offering advice for the illness vs wellness mentality and the need for clinically proven supplementation.

“Ageing gracefully means almost a gentle landing” Explains Gerald Quigley “I think of that word as accepting that over time our memory will be challenged and it will struggle often, and the more behaviours we can acknowledge and the nutritional support we can give brain function, that gracefully landing as we age will be as graceful as possible”

Sage advice

Discussing the topic further, the pair agree that clinically proven supplements, such as our Sibelius™: Sage, are imperative to supporting cognitive function. Sibelius™: Sage is a branded, traceable, scientifically evidenced and clinically proven dried sage extract, specially developed to support memory & alertness and maintain healthy brain function. What makes our Sage unique is the intense patented testing process Chronoscreen™ that ensures only the most functional extracts make their way to our customers.

  • Clinically Proven Cognitive Benefits
  • Immediacy of action - 1 hour
  • Global Regulatory Status
  • Samples available in multiple formats

Download the Sibelius™: Sage information sheet

Listen to the podcast here


Make room for mushrooms – Sibelius™: MyceliAid is here!

31 March 2021 (Oxford, UK) – Sibelius Natural Products has expanded its portfolio of natural ingredients with Sibelius™: MyceliAid – a wild-crafted, sustainably sourced chaga extract that supports immune function, promotes skin health and overall wellness.

Medicinal mushrooms saw skyrocketing growth in 2020 during the COVID-19 pandemic. And as unique varieties promoting new health benefits arrive on the market, shoppers are keen to explore them now more than ever.

“The pandemic has inevitably opened a lot of eyes and consumers have become increasingly aware  of their general health,” said Peter Leyland, CEO at Sibelius. “Functional mushrooms are being incorporated into consumers’ everyday routines for their many holistic wellness benefits”.

The rising popularity of medicinal mushrooms is also opening up new avenues of growth for savvy manufacturers. “We know that establishing quality and traceability in this category is critical, and that is why sourcing responsibly is one of our top priorities.” says Leyland.

Sibelius™: MyceliAid is a wild-crafted chaga mushroom grown on birch trees and carefully hand-picked by local farmers, on land protected by the government to ensure its longevity. Sibelius picked a distinguishable source of chaga with superior biological activity, as shown by their patented Chronoscreen™ platform – a proprietary assay for the identification of biologically active ingredients. This means that MyceliAid, other than having been analysed for Botanical ID, can be differentiated from other sources of chaga mushrooms grown in different regions.

As well as being sustainably grown, traceable and scientifically evidenced, MyceliAid comes as a water-dispersible powder suitable for several delivery forms, expanding the possibilities of chaga applications. Click here to find out more about MyceliAid.

About Sibelius Natural Products

Sibelius is a developer and marketer of high-value, clinically validated natural ingredients for use in dietary supplements, foods and beverages. The company is focused on building modern scientific evidence behind well-known botanicals, helping consumers to make informed decisions about the supplements they choose to purchase. Sibelius’ ingredient portfolio supports unique claims associated with cognition, sleep, anxiety, inflammation, cardiovascular health and men’s health. For more information, please fill in the form below:



Sibelius™:Chamomile featured in New Sleep and Relaxation Oral Spray

Sibelius Natural Products is excited to announce that its high-quality ingredient Sibelius™: Chamomile is featured in a new product from FutureYou Cambridge, targeting restful sleep and relaxation.

FutureYou Cambridge’s Restful Night+  is a relaxing blend of Sibelius™: Chamomile, our proprietary Roman chamomile extract, lavender oil and vitamin B6, developed to provide a calm nights’ sleep and stress relief naturally. This newly-introduced formulation is available in a mouth spray format, which enables the quick delivery and absorption of its actives for better sleep support.

Sibelius™:Chamomile derives from a proprietary, non-GMO source of Roman chamomile grown in the UK. Our herb grows sustainably and is harvested at a specific time to ensure the optimal content of bioactive compounds.

Roman chamomile (Chamaemelum nobile, syn. Anthemis nobilis) is one of the oldest known medicinal herbs, known for its soothing and relaxing benefits. Preclinical studies conducted with Sibelius™: Chamomile showed strong anti-inflammatory and immune-modulating activities, reducing the level of important inflammatory markers in both human adipocytes and neuroblastoma cell lines1.

In addition, a 4-week market observation study investigated the beneficial effects of Sibelius™: Chamomile on sleep in 18 healthy volunteers. The results showed significant improvements in sleep quality linked to a reduction in disruptive sleeping patterns.

Restful Night+ also contains lavender and peppermint oil, known for their calming properties, as well as a bioactive form of vitamin B6, a compound that plays a key role in supporting the nervous system and sleep2.

About Sibelius Natural Products

Sibelius is a developer and marketer of high-value, clinically validated natural ingredients for use in dietary supplements, foods and beverages. The company is focused on building modern scientific evidence behind well-known botanicals, helping consumers to make informed decisions about the supplements they choose to purchase. Sibelius’ ingredient portfolio supports unique claims associated with cognition, sleep, anxiety, inflammation, cardiovascular health and men’s health. For more information, please fill in the form below:



References

1. Russo, C et al. Effects of Salvia officinalis L. and Chamaemelum nobile (L.) extracts on inflammatory responses in two models of human cells: Primary subcutaneous adipocytes and neuroblastoma cell line (SK-N-SH). Journal of Ethnopharmacology. 2021; 268:113614.

2. Kennedy, DO. B Vitamins and the Brain: Mechanisms, Dose and Efficacy ¾ A Review. Nutrients. 2016; 8(2): 68.


Sibelius Wins an Innovate UK Smart Award to Uncover Complex Extracts' Mechanisms of Action

Oxford, UK, 10 February 2021 - Sibelius Natural Products is delighted to announce that the Company has won an Innovate UK Smart Award against very strong competition, as part of a collaborative application with the Clore Laboratory at the University of Buckingham. The award will support development of methods that help to uncover mechanisms of action that are responsible for the health benefits that complex natural products impart.

Sibelius is committed to investigating how its ingredients work, through molecular characterization and subsequent pre-clinical and clinical investigations as part of its proprietary Chronoscreen™ platform. The Company is constantly looking for new ways to complement these approaches to further its’ understanding on what triggers specific biological mechanisms.

Beyond knowing that an ingredient is safe and efficacious and can support health claims on consumer products, feedback from customers, distributors and partners has consistently highlighted a strong demand to understand both how and why an ingredient delivers its beneficial physiological effects.

“Sibelius has long been committed to bringing novel high-quality ingredients to the market and we truly believe that the science behind them makes a key difference” said Peter Leyland, CEO at Sibelius.

This new approach, when developed, will be utilized by scientists at Sibelius to support the identification of human proteins that are targeted by compounds within our ingredients, and therefore we can identify specific mechanisms-of-action that contribute towards the health benefits they impart.

In addition to providing a strong basis for novel IP protection, the new approach will also support continued development and science-based marketing of extracts. “Identifying the compounds present in complex extracts that can bind to human proteins, and what target proteins they bind to will provide invaluable insights” said Dr Kieron Edwards, CSO at Sibelius.

“This represents a great competitive advantage for finished product manufacturers and their formulators who will have access to a new level of understanding that will enable them to expand their pipeline with new evidence-based product innovations”, added Dr Edwards.

The method will provide Sibelius with a unique, world-leading capability to identify the putative active compounds and mechanisms of action for natural products at an unprecedented speed and scale. This represents a true category shift that delivers on real consumer needs for natural, plant-based solutions that are proven to work.

About Sibelius Natural Products

Sibelius Natural Products provides clinically validated and IP protected ingredients to the global dietary supplement, food & beverage industries. Dedicated to ongoing scientific research, rigorous quality management and thoughtful consumer education, Sibelius has pioneered the development of innovative natural ingredients such as Old English Sage and Roman Chamomile. The strong clinical research backing Sibelius’ ingredients has helped us support unique product claims for our customers associated with cognition, sleep & relaxation, inflammation, cardiovascular health and men’s health. For more information, please fill in the form below:



Sibelius™: Sage featured in New Cognitive Function and Memory Support supplement

Sibelius Natural Products has announced that its clinically substantiated ingredient Sibelius™: Sage is featured in a new product from Nootropics Depot, targeting cognitive skills and overall brain health.

The product, available in powder format, is a cognitive function and memory support game changer. The active ingredient, Sibelius™: Sage, has demonstrated tangible efficacy through in vitro and in vivo trials with researchers concluding that Sibelius™: Sage notably helps promote overall cognitive function.

Most recently, Sibelius™: Sage was the subject of a study published in the Journal of Ethnopharmacology, conducted on human in vitro data. The study investigated the effects of Sibelius™: Sage on inflammatory responses in human mature adipocytes and neuroblastoma cell lines. The results support the utilization of sage extract as a potentially effective therapeutic anti-inflammatory agent, which may contribute towards maintenance of long-term cognitive health.

About Sibelius™: Sage

Sibelius™: Sage is a patent-pending, nutritional ingredient that boosts cognitive performance. The ingredient has been clinically studied in healthy seniors, young adults and – for the first time – children, demonstrating its safety and efficacy. Sibelius™: Sage is both fast and effective, working within one hour and boosting cognitive performance.

About Sibelius Natural Products

Sibelius is a developer and marketer of high-value, clinically validated natural ingredients for use in dietary supplements, foods and beverages. The company is focused on building modern scientific evidence behind well-known botanicals, helping consumers to make informed decisions about the supplements they choose to purchase. Sibelius’ ingredient portfolio supports unique claims associated with cognition, sleep, anxiety, inflammation, cardiovascular health and men’s health. For more information, please fill in the form below: